Yang Liu - ESR13
NOVEL CONCEPTS IN SUPPORT OF CLINICAL MANAGEMENT OF AMR
A miniaturized isothermal nanocalorimetric platform for fast and accurate heat flow measurements
ESR13 will develop a miniaturized isothermal platform for nanocalorimetric measurements on bacteria evaluating their metabolic activity via the produced heat flow. The system will be interfaced with a microfluidic chip to dynamically apply reagents, nutrients, or drugs. Inhibitory effects of antimicrobial compounds will be evaluated aiming to distinguish drug-resistant strains from drug-susceptible ones. The sensitivity of the approach is expected to permit to diagnose presence of bacteria well before optical detection is possible.
Development of the new microfluidics technology; Nanocalorimetry to measure the metabolism of bacteria; Antimicrobial resistance study; FEM Simulations.
ESPCI Paris, France
MSc in Physical-Chemistry 2015
MSc in Microfluidics 2016